Microneedling With PDRN

Microneedling with PermaYouth (PDRN) at The Injectionist & Aesthetics is a next-level regenerative skin therapy designed to rebuild, repair, and rejuvenate from within. This advanced treatment pairs precision microneedling with PDRN (Polydeoxyribonucleotide) technology to deeply stimulate collagen, accelerate healing, and restore youthful radiance at the cellular level.

Unlike traditional microneedling, which focuses solely on mechanical collagen stimulation, Microneedling with PDRN enhances biological regeneration through DNA-based repair molecules that activate fibroblasts and boost cellular renewal. The result is firmer, smoother, more resilient skin that looks healthy, luminous, and revitalized.

What Is PDRN (PermaYouth)?

PermaYouth is a bio-revitalizing injectable and topical complex derived from purified salmon DNA fragments known as PDRN. Scientifically proven to promote tissue regeneration and cell turnover, PDRN is recognized for its ability to repair micro-damage, stimulate fibroblast activity, and improve skin elasticity. It also increases oxygenation and hydration within the dermis, helping the skin function as it did in its youth.

• Activates cellular repair and fibroblast regeneration
• Boosts collagen and elastin synthesis
• Improves texture, tone, and elasticity
• Reduces inflammation and supports healing
• Restores glow, smoothness, and firmness
• Safe for sensitive and post-inflammatory skin

How The Treatment Works

Microneedling creates micro-channels within the skin to trigger collagen induction while providing direct access for PermaYouth (PDRN) to be infused into the dermal layer. The PDRN molecules then bind to skin cell receptors and initiate powerful biological repair processes that improve both the structure and quality of the skin. This dual approach delivers immediate hydration and long-term dermal regeneration.

The treatment strengthens the skin’s barrier, reduces inflammation, and enhances tissue repair. Over time, fine lines soften, scars fade, and overall luminosity is restored as new collagen fibers develop and cellular metabolism improves.

Benefits of Microneedling with PDRN

• Stimulates collagen and elastin regeneration
• Accelerates healing and tissue renewal
• Improves skin density, tone, and hydration
• Refines pores and smooths uneven texture
• Minimizes fine lines and wrinkles
• Reduces redness, inflammation, and sensitivity
• Enhances glow and overall radiance

Microneedling with PDRN vs Standard Microneedling

Microneedling with PDRN provides both mechanical and biological rejuvenation, offering results that far surpass the collagen-only approach of standard microneedling. It is ideal for clients seeking true skin regeneration and repair.

The Injectionist Approach

Our clinicians are trained in advanced microneedling infusion techniques to optimize PDRN delivery and collagen activation. Each treatment is customized based on your skin type, depth requirements, and sensitivity. We use sterile, medical-grade devices and pharmaceutical-quality PermaYouth formulations to ensure precision, safety, and maximum regenerative response.

The treatment is suitable for all skin types, including those with acne scarring, dullness, or visible aging. It’s also an excellent post-laser or post-peel recovery option due to its anti-inflammatory and healing properties.

Results & Safety

• Treatment Time: 60 minutes
• Downtime: Mild redness for 12–48 hours
• Sessions: 3–4 spaced one month apart for best results
• Results: Brighter, firmer, smoother skin within days
• Longevity: Up to 9 months of collagen regeneration with maintenance treatments
• Safety: Biocompatible, non-toxic, and clinically validated for skin healing

Because PDRN accelerates cell renewal, downtime is minimal and results continue to evolve for several weeks post-treatment as collagen and elastin networks rebuild

Microneedling with PermaYouth (PDRN) is the ultimate regenerative therapy for skin renewal. It strengthens, restores, and revives, helping your skin perform like it did years younger. Ideal for dull, damaged, or aging complexions seeking powerful results through true bio-revitalization.

Available at The Injectionist & Aesthetics in Calgary and Edmonton.